MARBURG VIRUS DISEASE

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About

Marburg virus disease is a highly virulent disease that causes haemorrhagic fever, with a fatality ratio of up to 88%. It is in the same family as the virus that causes Ebola virus disease i.e family Filoviridae.

Origin

The virus was initially detected in 1967 after simultaneous outbreaks in Marburg and & Frankfurt in Germany; and in Belgrade, Serbia.

Cause

In this there is severe illness of humans and non-human primates caused by either of the two Marburgviruses: Marburg virus (MARV) and Ravn virus (RAVV). MVD is a viral hemorrhagic fever (VHF), and the clinical symptoms are indistinguishable from Ebola virus disease (EVD).
Marburgvirions contain non-infectious, linear nonsegmented, single-stranded RNA genomes.

Prevalance

Symptoms

The common symptoms of a virus are fever, headache, fatigue, abdominal pain and gingival haemorrhage.

Transmission

Fruit bats of the Pteropodidae Family are the key carriers of the disease. It typically infects humans following prolonged exposure to mines or caves inhabited by Rousettus bat colonies.
The home range of the fruit bats includes India, parts of Africa and the Middle-East, South-East Asian countries and some parts of Australia.
Human-to-human transmission takes place through direct contact with the blood, secretions, organs or other bodily fluids of infected people. Surfaces and materials contaminated with these fluids are other vital sources. Its incubation period ranges from two days to three weeks.

Vaccine and Treatment

There are no approved vaccines or antiviral treatments for the virus yet.
Early supportive care with rehydration and symptomatic treatment improves survival rates.