Researchers have developed an oral medication to treat diabetes which, they have reported in a new study, controls insulin levels while simultaneously reversing the inflammatory effects of the disease. The study has been published in Nature Biomedical Engineering.
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It cited two critical advantages of the drug over the standard treatment for diabetes.
Because it can be taken orally, it’s much simpler for the patient to stay compliant with his or her treatment.
It also addresses three major issues with diabetes at the same time: it helps control immediate blood glucose levels, restores pancreatic function, and re-establishes normal immunity in the pancreatic environment.
It’s all done within a nanocarrier composed of materials that our own bodies make — bile acids.
This means that the carrier itself has therapeutic effects that work with the loaded agent to reinstate normal metabolism in the short-term, and restore immune competence in the longer term.
Diabetes
Diabetes is a chronic disease that occurs either when the pancreas does not produce enough insulin or when the body cannot effectively use the insulin it produces.
Insulin is a hormone that regulates blood sugar.
Hyperglycaemia, or raised blood sugar, is a common effect of uncontrolled diabetes and over time leads to serious damage to many of the body's systems, especially the nerves and blood vessels.
Prevention: Simple lifestyle measures have been shown to be effective in preventing or delaying the onset of type 2 diabetes.