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Zika

3rd August, 2024

Zika

Source: THE STATESMAN

Disclaimer: Copyright infringement not intended.

Context:

  • Union Minister of State for Health and Family Welfare Anupriya Patel said the government of India has formulated an action plan for managing Zika virus Disease.

Details:

About Zika Virus:

Zika is a mosquito-borne virus identified in Uganda in 1947. The infection, often mild and self-limiting, poses significant risks to pregnant women and their fetuses, leading to microcephaly in newborns. It is also linked to Guillain-Barré syndrome, a rare nerve disorder causing muscle weakness and paralysis.

Virus

Zika virus (Flavivirus genus, Flaviviridae family)

Transmission

Aedes species mosquito (Aedes aegypti and Aedes albopictus)

Associated Diseases

Microcephaly in newborns, Guillain-Barré syndrome

First Discovery

Zika Forest, Uganda, 1947

First Human Case

1952

Significant Epidemic

Brazil, 2015

WHO Declaration

Public Health Emergency of International Concern (PHEIC), 2016

Spread in India (2018)

Gujarat, Madhya Pradesh, Rajasthan

Spread in India (2021)

Kerala, Maharashtra

Microcephaly in India

Not recorded

 Microdetails about the Zika Virus:

Virus Structure

Single-stranded RNA virus, Flaviviridae family

Lineages

Asian and African lineages

Hosts

African lineage: Monkeys and apes (primary), humans (secondary)

Asian lineage: Humans (primary)

Structural Proteins

Capsid (C), membrane (M), envelope (E)

Nonstructural Proteins

Seven proteins aiding in genome replication, packaging, and host manipulation

Discovery Technique

Cryo-electron microscopy revealed near-atomic structure for the first time

Transmission Modes

Infected Aedes aegypti mosquito bite, sexual contact, blood transfusion, organ transplantation, congenital infection

Testing

Detection of viral RNA in blood, saliva, urine, cerebrospinal fluid, amniotic fluid, semen, and breast milk

Symptoms

Incubation: 3-12 days post-bite 

Common: Maculopapular rash, arthralgia, fatigue, conjunctivitis, myalgia, headache

Less Common Symptoms

Retro-orbital pain, gastrointestinal symptoms

Treatment

No vaccine/preventative treatment

Symptomatic: Hydration, pain relief, antihistamines

Control Measures

Regular vector surveillance, integrated vector management

Integrated Vector Management

Environmental modification, protective clothing, repellents, biological control (larvivorous fish, Bacillus thuringiensis), chemical control (larvicides: temephos, adulticides: pyrethrum, malathion)

 MUST READ ARTICLES

Zika Virus 

MOSQUITO-BORNE DISEASES 

WEST NILE VIRUS

ALL YOU NEED TO KNOW ABOUT VIRUSES

Source:

https://www.thestatesman.com/india/action-plan-ready-to-tackle-zika-virus-disease-anupriya-patel-1503326392.html#google_vignette

https://www.who.int/news-room/fact-sheets/detail/zika-virus

https://my.clevelandclinic.org/health/diseases/16077-zika-virus

PRACTICE QUESTION

  1. With reference to the Zika Virus, consider the following statements:
  2. Zika Virus is transmitted through the bite of the Aedes aegypti mosquito.
  3. Zika Virus infection during pregnancy can cause microcephaly and other severe fetal brain defects.
  4. There is currently an effective vaccine available for Zika Virus.

Which of the statements given above is/are correct?

(a) 1 only

(b) 1 and 2 only

(c) 2 and 3 only

(d) 1, 2, and 3

Answer: (b)