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Details:
About Zika Virus:
Zika is a mosquito-borne virus identified in Uganda in 1947. The infection, often mild and self-limiting, poses significant risks to pregnant women and their fetuses, leading to microcephaly in newborns. It is also linked to Guillain-Barré syndrome, a rare nerve disorder causing muscle weakness and paralysis.
Virus |
Zika virus (Flavivirus genus, Flaviviridae family) |
Transmission |
Aedes species mosquito (Aedes aegypti and Aedes albopictus) |
Associated Diseases |
Microcephaly in newborns, Guillain-Barré syndrome |
First Discovery |
Zika Forest, Uganda, 1947 |
First Human Case |
1952 |
Significant Epidemic |
Brazil, 2015 |
WHO Declaration |
Public Health Emergency of International Concern (PHEIC), 2016 |
Spread in India (2018) |
Gujarat, Madhya Pradesh, Rajasthan |
Spread in India (2021) |
Kerala, Maharashtra |
Microcephaly in India |
Not recorded |
Microdetails about the Zika Virus:
Virus Structure |
Single-stranded RNA virus, Flaviviridae family |
Lineages |
Asian and African lineages |
Hosts |
African lineage: Monkeys and apes (primary), humans (secondary) Asian lineage: Humans (primary) |
Structural Proteins |
Capsid (C), membrane (M), envelope (E) |
Nonstructural Proteins |
Seven proteins aiding in genome replication, packaging, and host manipulation |
Discovery Technique |
Cryo-electron microscopy revealed near-atomic structure for the first time |
Transmission Modes |
Infected Aedes aegypti mosquito bite, sexual contact, blood transfusion, organ transplantation, congenital infection |
Testing |
Detection of viral RNA in blood, saliva, urine, cerebrospinal fluid, amniotic fluid, semen, and breast milk |
Symptoms |
Incubation: 3-12 days post-bite Common: Maculopapular rash, arthralgia, fatigue, conjunctivitis, myalgia, headache |
Less Common Symptoms |
Retro-orbital pain, gastrointestinal symptoms |
Treatment |
No vaccine/preventative treatment Symptomatic: Hydration, pain relief, antihistamines |
Control Measures |
Regular vector surveillance, integrated vector management |
Integrated Vector Management |
Environmental modification, protective clothing, repellents, biological control (larvivorous fish, Bacillus thuringiensis), chemical control (larvicides: temephos, adulticides: pyrethrum, malathion) |
MUST READ ARTICLES
ALL YOU NEED TO KNOW ABOUT VIRUSES
Source:
https://www.who.int/news-room/fact-sheets/detail/zika-virus
https://my.clevelandclinic.org/health/diseases/16077-zika-virus
PRACTICE QUESTION
Which of the statements given above is/are correct? (a) 1 only (b) 1 and 2 only (c) 2 and 3 only (d) 1, 2, and 3 Answer: (b) |
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